No. 5: Lexus RX 400h

EPA-estimated mileage: 27/24

Though it's a luxury model, the RX 400h's price premium is a mere 10 percent over the gas-only RX 350. Combined with a 50 percent city mileage improvement and 4 percent highway bump, it's a compelling package overall. The RX is similar to the Toyota Highlander Hybrid, which has a lower overall price and 1 mpg higher highway mileage, but that model's higher price premium gives it a lower rank. With optional AWD, the RX 400h (26/24 mpg) is an even better deal, with mileage improvements of 53 percent and 9 percent compared to the all-wheel-drive RX 350.
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